Mus musculus Gene: Foxs1
InnateDB Gene IDBG-209923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxs1
Gene Name forkhead box S1
Synonyms Fkh3; Fkhl18; FREAC10
Species Mus musculus
Ensembl Gene ENSMUSG00000074676
Encoded Proteins
forkhead box S1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179772:
The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152931898-152933208
Strand Reverse strand
Band H1
ENSMUST00000099200 ENSMUSP00000096806
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001503 ossification
GO:0001568 blood vessel development
GO:0001569 patterning of blood vessels
GO:0001756 somitogenesis
GO:0001946 lymphangiogenesis
GO:0001974 blood vessel remodeling
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007219 Notch signaling pathway
GO:0008286 insulin receptor signaling pathway
GO:0030199 collagen fibril organization
GO:0035050 embryonic heart tube development
GO:0040018 positive regulation of multicellular organism growth
GO:0043010 camera-type eye development
GO:0043066 negative regulation of apoptotic process
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046620 regulation of organ growth
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048343 paraxial mesodermal cell fate commitment
GO:0048844 artery morphogenesis
GO:0050880 regulation of blood vessel size
GO:0050885 neuromuscular process controlling balance
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060038 cardiac muscle cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q61574
UniProt Splice Variant
Entrez Gene 14239
UniGene Mm.205798
RefSeq NM_010226
MGI ID MGI:95546
MGI Symbol Foxs1
EMBL AK077935 AK152669 BC096604 BC131937 BC131939 X71941
GenPept AAH96604 AAI31938 AAI31940 BAC37074 BAE31404 CAA50743
RNA Seq Atlas 14239