Version 5.4
Mus musculus Gene: Rpl23
Summary
InnateDB Gene IDBG-210357.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rpl23
Gene Name ribosomal protein L23
Synonyms 2810009A01Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000071415
Encoded Proteins
IDBP-210359
ribosomal protein L23
IDBP-537264
ribosomal protein L23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125691:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:97777527-97782437
Strand Reverse strand
Band D
Transcripts
ENSMUST00000103146 ENSMUSP00000099435
ENSMUST00000151118
ENSMUST00000150955
ENSMUST00000151965
ENSMUST00000128801 ENSMUSP00000117316
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 35 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 113 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125691
View Gene Order
ENSBTAG00000003229
Not yet available
Pathways
NETPATH
REACTOME
REACT_253640
Peptide chain elongation pathway
REACT_254308
Translation pathway
REACT_231519
Eukaryotic Translation Termination pathway
REACT_198522
Nonsense-Mediated Decay (NMD) pathway
REACT_247926
Metabolism of proteins pathway
REACT_198528
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_198524
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_229570
Cap-dependent Translation Initiation pathway
REACT_262064
Eukaryotic Translation Initiation pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_232254
Eukaryotic Translation Elongation pathway
REACT_249044
Formation of a pool of free 40S subunits pathway
REACT_233572
Gene Expression pathway
REACT_259469
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_262078
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
KEGG
mmu03010
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_79
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_75768
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_75822
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_2085
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_1797
Formation of a pool of free 40S subunits pathway
REACT_1986
Eukaryotic Translation Termination pathway
REACT_1404
Peptide chain elongation pathway
REACT_1477
Eukaryotic Translation Elongation pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_9491
Viral mRNA Translation pathway
REACT_2159
Eukaryotic Translation Initiation pathway
REACT_6167
Influenza Infection pathway
REACT_75886
Nonsense-Mediated Decay (NMD) pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_2099
Cap-dependent Translation Initiation pathway
REACT_6145
Influenza Life Cycle pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_221721
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_246268
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_202833
Peptide chain elongation pathway
REACT_225310
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_226022
Gene Expression pathway
REACT_218564
Eukaryotic Translation Initiation pathway
REACT_225918
Cap-dependent Translation Initiation pathway
REACT_222208
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_216229
Formation of a pool of free 40S subunits pathway
REACT_209048
Translation pathway
REACT_202903
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_213782
Metabolism of proteins pathway
REACT_222777
Nonsense-Mediated Decay (NMD) pathway
REACT_201931
Eukaryotic Translation Termination pathway
REACT_225811
Eukaryotic Translation Elongation pathway
KEGG
hsa03010
Ribosome pathway
INOH
PID NCI
p53regulationpathway
p53 pathway
Cross-References
SwissProt P62830
TrEMBL
UniProt Splice Variant
Entrez Gene 65019
UniGene
RefSeq NM_022891 XM_003688758 XM_003689218 XM_006543376
OMIM
CCDS CCDS25331
HPRD
IMGT
MGI ID MGI:1929455
MGI Symbol Rpl23
EMBL AF158022 AF287271 AK002579 AK010680 AK012694 AK018730 AK150671 AK168133 BC025918 BC081448
GenPept AAD42413 AAF88071 AAH25918 AAH81448 BAB22203 BAB27112 BAB28415 BAB31373 BAE29753 BAE40102
RNA Seq Atlas 100044627 100862455 65019

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca