InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL23

Summary

InnateDB Gene

IDBG-45005.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL23

Gene Name

ribosomal protein L23

Synonyms

L23; rpL17

Species

Homo sapiens

Ensembl Gene

ENSG00000125691

Encoded Proteins

IDBP-45007

ribosomal protein L23

IDBP-757933

IDBP-241801

ribosomal protein L23

IDBP-241803

ribosomal protein L23

IDBP-474081

ribosomal protein L23

IDBP-761573

IDBP-763619

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:38847865-38853843

Strand

Reverse strand

Band

q12

Transcripts

ENST00000378096	ENSP00000367336
ENST00000245857	ENSP00000463014
ENST00000394333	ENSP00000377866
ENST00000394332	ENSP00000377865
ENST00000479035	ENSP00000420311
ENST00000470646	ENSP00000463894
ENST00000577760
ENST00000584912
ENST00000577407	ENSP00000462773
ENST00000584056
ENST00000584583

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	151 [view]
Protein-Protein	151 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006610	ribosomal protein import into nucleus
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0070062	extracellular vesicular exosome