Version 5.4
Mus musculus Gene: Myl9
Summary
InnateDB Gene IDBG-210979.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl9
Gene Name myosin, light polypeptide 9, regulatory
Synonyms AI327049; MLC20; Mylc2c; RLC-C
Species Mus musculus
Ensembl Gene ENSMUSG00000067818
Encoded Proteins
IDBP-210981
myosin, light polypeptide 9, regulatory
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101335:
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:156775420-156781658
Strand Forward strand
Band H1
Transcripts
ENSMUST00000088552 ENSMUSP00000085913
ENSMUST00000145299
ENSMUST00000132985
ENSMUST00000131622
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0001725 stress fiber
GO:0016460 myosin II complex
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101335
View Gene Order
ENSBTAG00000011473
Not yet available
Pathways
NETPATH
REACTOME
REACT_243939
EPHA-mediated growth cone collapse pathway
REACT_235059
Smooth Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
REACT_246650
Sema4D induced cell migration and growth-cone collapse pathway
REACT_258158
EPH-Ephrin signaling pathway
REACT_261444
Axon guidance pathway
REACT_234744
Sema4D in semaphorin signaling pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
KEGG
mmu04530
Tight junction pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04670
Leukocyte transendothelial migration pathway
mmu04510
Focal adhesion pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
REACT_19277
Sema4D induced cell migration and growth-cone collapse pathway
REACT_19259
Sema4D in semaphorin signaling pathway
REACT_20558
Smooth Muscle Contraction pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_18266
Axon guidance pathway
REACT_228063
EPHA-mediated growth cone collapse pathway
REACT_228170
EPH-Ephrin signaling pathway
REACT_17044
Muscle contraction pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04670
Leukocyte transendothelial migration pathway
hsa04530
Tight junction pathway
hsa04510
Focal adhesion pathway
hsa04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
ilk_pathway
Integrin-linked kinase signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_172118 XM_006500453
OMIM
CCDS CCDS50779
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca