Version 5.4
| Mus musculus Gene: Bub3 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-211014.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Bub3 | ||||||||||||||||||||||
| Gene Name | budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) | ||||||||||||||||||||||
| Synonyms | AU019800; AU021329; AU043350; AW146323; C78067 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000066979 | ||||||||||||||||||||||
| Encoded Proteins |
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154473:
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 7:131560391-131571898 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | F3 | ||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Cell Cycle, Mitotic pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Cell Cycle pathway
APC/C-mediated degradation of cell cycle proteins pathway
M Phase pathway
Cell Cycle Checkpoints pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Regulation of mitotic cell cycle pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
Mitotic Spindle Checkpoint pathway
Mitotic Anaphase pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
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| KEGG |
Cell cycle pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
APC/C-mediated degradation of cell cycle proteins pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Regulation of mitotic cell cycle pathway
Cell Cycle pathway
Mitotic Spindle Checkpoint pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Cell Cycle Checkpoints pathway
Mitotic Metaphase and Anaphase pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
M Phase pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Separation of Sister Chromatids pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Cell Cycle pathway
Mitotic Spindle Checkpoint pathway
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components pathway
Regulation of mitotic cell cycle pathway
APC/C-mediated degradation of cell cycle proteins pathway
Resolution of Sister Chromatid Cohesion pathway
Inactivation of APC/C via direct inhibition of the APC/C complex pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
Mitotic Prometaphase pathway
Cell Cycle Checkpoints pathway
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| KEGG |
Cell cycle pathway
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| INOH | |||||||||||||||||||||||
| PID NCI |
p73 transcription factor network
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| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Mm.419467 | ||||||||||||||||||||||
| RefSeq | NM_009774 XM_006507270 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS40160 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||