Version 5.4
Homo sapiens Gene: CINP
Summary
InnateDB Gene IDBG-21107.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CINP
Gene Name cyclin-dependent kinase 2 interacting protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100865
Encoded Proteins
IDBP-21109
cyclin-dependent kinase 2 interacting protein
IDBP-587236
cyclin-dependent kinase 2 interacting protein
IDBP-599866
cyclin-dependent kinase 2 interacting protein
IDBP-595722
cyclin-dependent kinase 2 interacting protein
IDBP-585270
cyclin-dependent kinase 2 interacting protein
IDBP-600323
cyclin-dependent kinase 2 interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene interacts with CDK2, MCM5, and CDC7, and is associated with the origin recognition complex protein ORC2. It acts as a homodimer and is involved in replication and ATR-mediated checkpoint signaling. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:102341102-102362916
Strand Reverse strand
Band q32.31
Transcripts
ENST00000216756 ENSP00000216756
ENST00000559504 ENSP00000453846
ENST00000559514 ENSP00000453839
ENST00000560326
ENST00000536961 ENSP00000442057
ENST00000541568 ENSP00000442377
ENST00000561468
ENST00000558764 ENSP00000452982
ENST00000558523
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0007049 cell cycle
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021276
View Gene Order
ENSBTAG00000010995
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.129634 Hs.734384 Hs.736782
RefSeq NM_032630 XM_005267753
HUGO
OMIM
CCDS CCDS9972
HPRD 16715
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca