Version 5.4
| Mus musculus Gene: Ppy | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-212445.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Ppy | ||||||
| Gene Name | pancreatic polypeptide | ||||||
| Synonyms | AV061413; IGSPP; PP | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000017316 | ||||||
| Encoded Proteins |
pancreatic polypeptide
pancreatic polypeptide
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108849:
This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 11:102099930-102101319 | ||||||
| Strand | Reverse strand | ||||||
| Band | D | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
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| KEGG | |||||||
| INOH |
GPCR signaling pathway
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| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
G alpha (i) signalling events pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
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| KEGG | |||||||
| INOH |
GPCR signaling pathway
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| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | P10601 | ||||||
| TrEMBL | Q496X5 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 19064 | ||||||
| UniGene | Mm.1269 | ||||||
| RefSeq | NM_008918 | ||||||
| OMIM | |||||||
| CCDS | CCDS25486 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:97753 | ||||||
| MGI Symbol | Ppy | ||||||
| EMBL | AK131852 BC099881 BC100676 BC101946 CH466558 M18208 | ||||||
| GenPept | AAA39967 AAH99881 AAI00677 AAI01947 BAE20831 EDL34086 | ||||||
| RNA Seq Atlas | 19064 | ||||||