Mus musculus Gene: Pfdn4
Summary
InnateDB Gene IDBG-213248.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfdn4
Gene Name prefoldin 4
Synonyms 0610025M10Rik; 1810063B06Rik; C-1; C1; Pfd4;
Species Mus musculus
Ensembl Gene ENSMUSG00000052033
Encoded Proteins
prefoldin 4
prefoldin 4
prefoldin 4
prefoldin 4
prefoldin 4
prefoldin 4
prefoldin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101132:
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:170496428-170519123
Strand Forward strand
Band H3
Transcripts
ENSMUST00000075087 ENSMUSP00000074596
ENSMUST00000063682 ENSMUSP00000070596
ENSMUST00000109148 ENSMUSP00000104776
ENSMUST00000109147 ENSMUSP00000104775
ENSMUST00000136839 ENSMUSP00000130383
ENSMUST00000139328 ENSMUSP00000127453
ENSMUST00000170167 ENSMUSP00000131911
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016272 prefoldin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E9Q4Q8 E9Q8R1 Q3UWL8 Q6P0X1
UniProt Splice Variant
Entrez Gene 109054
UniGene Mm.399311
RefSeq NM_001110152 NM_001013369 NM_001199902
OMIM
CCDS CCDS50807 CCDS50808 CCDS57190
HPRD
IMGT
MGI ID MGI:1923512
MGI Symbol Pfdn4
EMBL AK136249 AL935134 AL954701 BC065407 BC147673 BC147674
GenPept AAH65407 AAI47674 AAI47675 BAE22896
RNA Seq Atlas 109054