Mus musculus Gene: Cstf1
Summary
InnateDB Gene IDBG-213287.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cstf1
Gene Name cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms 1700057K18Rik; AI788832;
Species Mus musculus
Ensembl Gene ENSMUSG00000027498
Encoded Proteins
cleavage stimulation factor, 3' pre-RNA, subunit 1
cleavage stimulation factor, 3' pre-RNA, subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101138:
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3\'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5\' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:172370681-172382448
Strand Forward strand
Band H3
Transcripts
ENSMUST00000116375 ENSMUSP00000112076
ENSMUST00000151511 ENSMUSP00000121178
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA 3'-end processing pathway
mRNA Splicing pathway
Processing of Capped Intronless Pre-mRNA pathway
Processing of Intronless Pre-mRNAs pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
mRNA surveillance pathway pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
mRNA 3'-end processing pathway
RNA Polymerase II Transcription Termination pathway
Processing of Intronless Pre-mRNAs pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA Splicing pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
mRNA surveillance pathway pathway
INOH
PID BIOCARTA
Polyadenylation of mrna [Biocarta view]
PID NCI
BARD1 signaling events
Cross-References
SwissProt Q99LC2
TrEMBL A2APA3
UniProt Splice Variant
Entrez Gene 67337
UniGene Mm.26944 Mm.409948 Mm.447539
RefSeq NM_024199 XM_006500072
OMIM
CCDS CCDS17130
HPRD
IMGT
MGI ID MGI:1914587
MGI Symbol Cstf1
EMBL AK011943 AK050686 AK078667 AK145001 AL833787 BC003440
GenPept AAH03440 BAB27929 BAC34379 BAC37353 BAE26180
RNA Seq Atlas 67337