Version 5.4
Mus musculus Gene: Rab22a
Summary
InnateDB Gene IDBG-213398.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab22a
Gene Name RAB22A, member RAS oncogene family
Synonyms 3732413A17Rik; AI662177; AW319644; AW550514; E130120E14Rik; Rab22
Species Mus musculus
Ensembl Gene ENSMUSG00000027519
Encoded Proteins
IDBP-213400
RAB22A, member RAS oncogene family
IDBP-263086
RAB22A, member RAS oncogene family
IDBP-536538
RAB22A, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124209:
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:173659760-173707343
Strand Forward strand
Band H3
Transcripts
ENSMUST00000029024 ENSMUSP00000029024
ENSMUST00000109110 ENSMUSP00000104738
ENSMUST00000142820 ENSMUSP00000122799
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0006913 nucleocytoplasmic transport
GO:0007032 endosome organization
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0001726 ruffle
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124209
View Gene Order
ENSBTAG00000018053
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D6RFT6
UniProt Splice Variant
Entrez Gene 19334
UniGene Mm.275304 Mm.401808 Mm.407219
RefSeq NM_024436
OMIM
CCDS CCDS38352
HPRD
IMGT
MGI ID MGI:105072
MGI Symbol Rab22a
EMBL AL845503
GenPept
RNA Seq Atlas 19334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca