Version 5.4
Homo sapiens Gene: RAB22A
Summary
InnateDB Gene IDBG-82535.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB22A
Gene Name RAB22A, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124209
Encoded Proteins
IDBP-82537
RAB22A, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:58309696-58367507
Strand Forward strand
Band q13.32
Transcripts
ENST00000244040 ENSP00000244040
ENST00000488949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0006913 nucleocytoplasmic transport
GO:0007032 endosome organization
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0001726 ruffle
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027519
View Gene Order
ENSBTAG00000018053
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9UL26
TrEMBL Q96IY7
UniProt Splice Variant
Entrez Gene 57403
UniGene Hs.529044 Hs.603208 Hs.606077 Hs.642291 Hs.650035
RefSeq NM_020673 XM_005260469
HUGO HGNC:9764
OMIM 612966
CCDS CCDS33497
HPRD
IMGT
EMBL AF091034 AF125104 AJ276210 AK091180 AL035455 BC007036 BC015710 BC063457 BT007046 CH471077
GenPept AAF00047 AAH07036 AAH15710 AAH63457 AAL75941 AAP35695 BAG52298 CAC10538 CAC15020 EAW75496 EAW75497
RNA Seq Atlas 57403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca