Mus musculus Gene: Cacng4
Summary
InnateDB Gene IDBG-213727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cacng4
Gene Name calcium channel, voltage-dependent, gamma subunit 4
Synonyms AI413107; AW491861;
Species Mus musculus
Ensembl Gene ENSMUSG00000020723
Encoded Proteins
calcium channel, voltage-dependent, gamma subunit 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075461:
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:107732357-107794557
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000021066 ENSMUSP00000021066
ENSMUST00000134076
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005245 voltage-gated calcium channel activity
Biological Process
GO:0019226 transmission of nerve impulse
GO:0070588 calcium ion transmembrane transport
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Cellular Component
GO:0005891 voltage-gated calcium channel complex
GO:0016021 integral component of membrane
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
Neuronal System pathway
Transmission across Chemical Synapses pathway
KEGG
MAPK signaling pathway pathway
Cardiac muscle contraction pathway
Hypertrophic cardiomyopathy (HCM) pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Dilated cardiomyopathy pathway
INOH
GPCR Dopamine D1like receptor signaling pathway pathway
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Neuronal System pathway
Trafficking of AMPA receptors pathway
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
KEGG
MAPK signaling pathway pathway
Cardiac muscle contraction pathway
Hypertrophic cardiomyopathy (HCM) pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Dilated cardiomyopathy pathway
INOH
GPCR Dopamine D1like receptor signaling pathway pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9JJV4
TrEMBL A2AAU2
UniProt Splice Variant
Entrez Gene 54377
UniGene Mm.103724 Mm.398518
RefSeq NM_019431
OMIM
CCDS CCDS25571
HPRD
IMGT
MGI ID MGI:1859167
MGI Symbol Cacng4
EMBL AJ272045 BC138503 BC138506
GenPept AAI38504 AAI38507 CAB86386
RNA Seq Atlas 54377