Version 5.4
Mus musculus Gene: Pcyt2
Summary
InnateDB Gene IDBG-214856.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcyt2
Gene Name phosphate cytidylyltransferase 2, ethanolamine
Synonyms 1110033E03Rik; ET
Species Mus musculus
Ensembl Gene ENSMUSG00000025137
Encoded Proteins
IDBP-214858
phosphate cytidylyltransferase 2, ethanolamine
IDBP-269285
phosphate cytidylyltransferase 2, ethanolamine
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185813:
This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120610087-120617936
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026129 ENSMUSP00000026129
ENSMUST00000106188 ENSMUSP00000101794
ENSMUST00000106187
ENSMUST00000124504
ENSMUST00000143502
ENSMUST00000134671
ENSMUST00000124468
ENSMUST00000142049
ENSMUST00000145356
ENSMUST00000126723
ENSMUST00000126148
ENSMUST00000160059
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004306 ethanolamine-phosphate cytidylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0009058 biosynthetic process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185813
View Gene Order
ENSBTAG00000001868
Not yet available
Pathways
NETPATH
REACTOME
REACT_199009
Synthesis of PE pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120919
Synthesis of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
REACT_202421
Glycerophospholipid biosynthesis pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_219139
Metabolism pathway
REACT_218329
Phospholipid metabolism pathway
REACT_222433
Synthesis of PE pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.21439
RefSeq NM_024229 XM_006534069 XM_006534070 XM_006534071
OMIM
CCDS CCDS25747
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca