Homo sapiens Gene: OPRK1
Summary
InnateDB Gene IDBG-21599.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OPRK1
Gene Name opioid receptor, kappa 1
Synonyms K-OR-1; KOR; KOR-1; OPRK;
Species Homo sapiens
Ensembl Gene ENSG00000082556
Encoded Proteins
opioid receptor, kappa 1
opioid receptor, kappa 1
opioid receptor, kappa 1
opioid receptor, kappa 1
opioid receptor, kappa 1
opioid receptor, kappa 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:53225716-53251697
Strand Reverse strand
Band q11.23
Transcripts
ENST00000265572 ENSP00000265572
ENST00000522508 ENSP00000428231
ENST00000524278 ENSP00000430923
ENST00000520287 ENSP00000429706
ENST00000612786 ENSP00000483000
ENST00000613482 ENSP00000478453
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004985 opioid receptor activity
GO:0005515 protein binding
GO:0038048 dynorphin receptor activity
Biological Process
GO:0006955 immune response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0007600 sensory perception
GO:0007610 behavior
GO:0007626 locomotory behavior
GO:0019233 sensory perception of pain
GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0038003 opioid receptor signaling pathway
GO:0046877 regulation of saliva secretion
GO:0051607 defense response to virus
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Peptide ligand-binding receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
GPCR ligand binding pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
Repression of pain sensation by the transcriptional regulator dream [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 4986
UniGene Hs.106795 Hs.693545
RefSeq NM_000912 NM_001282904 XM_005251252
HUGO HGNC:8154
OMIM 165196
CCDS CCDS64895 CCDS6152
HPRD 01309
IMGT
EMBL
GenPept
RNA Seq Atlas 4986