Version 5.4
Homo sapiens Gene: OPRK1
Summary
InnateDB Gene IDBG-21599.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OPRK1
Gene Name opioid receptor, kappa 1
Synonyms K-OR-1; KOR; KOR-1; OPRK
Species Homo sapiens
Ensembl Gene ENSG00000082556
Encoded Proteins
IDBP-21601
opioid receptor, kappa 1
IDBP-477588
opioid receptor, kappa 1
IDBP-477441
opioid receptor, kappa 1
IDBP-482681
opioid receptor, kappa 1
IDBP-809762
opioid receptor, kappa 1
IDBP-809765
opioid receptor, kappa 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:53225716-53251697
Strand Reverse strand
Band q11.23
Transcripts
ENST00000265572 ENSP00000265572
ENST00000522508 ENSP00000428231
ENST00000524278 ENSP00000430923
ENST00000520287 ENSP00000429706
ENST00000612786 ENSP00000483000
ENST00000613482 ENSP00000478453
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004985 opioid receptor activity
GO:0005515 protein binding
GO:0038048 dynorphin receptor activity
Biological Process
GO:0006955 immune response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0007600 sensory perception
GO:0007610 behavior
GO:0007626 locomotory behavior
GO:0019233 sensory perception of pain
GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0038003 opioid receptor signaling pathway
GO:0046877 regulation of saliva secretion
GO:0051607 defense response to virus
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025905
View Gene Order
ENSBTAG00000000914
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.106795 Hs.693545
RefSeq NM_000912 NM_001282904 XM_005251252
HUGO
OMIM
CCDS CCDS6152 CCDS64895
HPRD 01309
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca