Homo sapiens Gene: TGS1
Summary
InnateDB Gene IDBG-22149.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TGS1
Gene Name trimethylguanosine synthase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137574
Encoded Proteins
trimethylguanosine synthase 1
trimethylguanosine synthase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:55773142-55825448
Strand Forward strand
Band q12.1
Transcripts
ENST00000260129 ENSP00000260129
ENST00000523948 ENSP00000430467
ENST00000519494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0016740 transferase activity
GO:0071164 RNA trimethylguanosine synthase activity
Biological Process
GO:0000387 spliceosomal snRNP assembly
GO:0001510 RNA methylation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009452 7-methylguanosine RNA capping
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0022613 ribonucleoprotein complex biogenesis
GO:0034660 ncRNA metabolic process
GO:0036261 7-methylguanosine cap hypermethylation
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0071167 ribonucleoprotein complex import into nucleus
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0015030 Cajal body
GO:0030532 small nuclear ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Circadian Clock pathway
Activation of gene expression by SREBF (SREBP) pathway
Metabolism of lipids and lipoproteins pathway
REV-ERBA represses gene expression pathway
Mitochondrial biogenesis pathway
PPARA activates gene expression pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
Generic Transcription Pathway pathway
RORA activates circadian gene expression pathway
Orphan transporters pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Metabolism of non-coding RNA pathway
Transcriptional activation of mitochondrial biogenesis pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
snRNP Assembly pathway
Metabolism pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Gene Expression pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96RS0
TrEMBL E5RJW7
UniProt Splice Variant
Entrez Gene 96764
UniGene Hs.335068 Hs.606306
RefSeq NM_024831 XM_005251328 XM_006716485 XM_006716486
HUGO HGNC:17843
OMIM 606461
CCDS CCDS34894
HPRD
IMGT
EMBL AC018607 AC100817 AF286340 AF432215 AK026648 AY028423 AY534911 BC011999
GenPept AAH11999 AAK27730 AAK83025 AAL99922 AAT02709 BAB15516
RNA Seq Atlas 96764