Version 5.4
Homo sapiens Gene: SDR16C5
Summary
InnateDB Gene IDBG-22540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDR16C5
Gene Name short chain dehydrogenase/reductase family 16C, member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170786
Encoded Proteins
IDBP-22542
short chain dehydrogenase/reductase family 16C, member 5
IDBP-236903
short chain dehydrogenase/reductase family 16C, member 5
IDBP-479851
short chain dehydrogenase/reductase family 16C, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:56300010-56320776
Strand Reverse strand
Band q12.1
Transcripts
ENST00000303749 ENSP00000307607
ENST00000396721 ENSP00000379947
ENST00000522671 ENSP00000431010
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004745 retinol dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0043616 keratinocyte proliferation
GO:0050908 detection of light stimulus involved in visual perception
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028236
View Gene Order
ENSBTAG00000018570
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00830
Retinol metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q8N3Y7
TrEMBL
UniProt Splice Variant
Entrez Gene 195814
UniGene Hs.608211
RefSeq NM_138969
HUGO HGNC:30311
OMIM 608989
CCDS CCDS6167
HPRD 12351
IMGT
EMBL AB083038 AK057667 AK294634 AY444559 BC037219 BC064525 CH471068
GenPept AAH37219 AAH64525 AAS68535 BAB71545 BAB91014 BAG57813 EAW86780
RNA Seq Atlas 195814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca