Homo sapiens Gene: SDR16C5
Summary
InnateDB Gene IDBG-22540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDR16C5
Gene Name short chain dehydrogenase/reductase family 16C, member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170786
Encoded Proteins
short chain dehydrogenase/reductase family 16C, member 5
short chain dehydrogenase/reductase family 16C, member 5
short chain dehydrogenase/reductase family 16C, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:56300010-56320776
Strand Reverse strand
Band q12.1
Transcripts
ENST00000303749 ENSP00000307607
ENST00000396721 ENSP00000379947
ENST00000522671 ENSP00000431010
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004745 retinol dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0043616 keratinocyte proliferation
GO:0050908 detection of light stimulus involved in visual perception
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Retinol metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.608211
RefSeq NM_138969
HUGO
OMIM
CCDS CCDS6167
HPRD 12351
IMGT
EMBL
GenPept
RNA Seq Atlas