Version 5.4
Homo sapiens Gene: NUPR1
Summary
InnateDB Gene IDBG-22854.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUPR1
Gene Name nuclear protein, transcriptional regulator, 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176046
Encoded Proteins
IDBP-22856
nuclear protein, transcriptional regulator, 1
IDBP-239156
nuclear protein, transcriptional regulator, 1
IDBP-754264
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:28532708-28539174
Strand Reverse strand
Band p11.2
Transcripts
ENST00000324873 ENSP00000315559
ENST00000395641 ENSP00000379003
ENST00000567646 ENSP00000456597
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0002526 acute inflammatory response
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006461 protein complex assembly
GO:0006473 protein acetylation
GO:0008584 male gonad development
GO:0009636 response to toxic substance
GO:0016049 cell growth
GO:0031401 positive regulation of protein modification process
GO:0035914 skeletal muscle cell differentiation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 positive regulation of apoptotic process
GO:0045786 negative regulation of cell cycle
GO:0048147 negative regulation of fibroblast proliferation
GO:2000194 regulation of female gonad development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030717
View Gene Order
ENSBTAG00000018016
Not yet available
Pathways
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001042483 NM_012385
HUGO
OMIM
CCDS CCDS10634 CCDS42137
HPRD 17814
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca