Homo sapiens Gene: CAPN14
Summary
InnateDB Gene IDBG-232114.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPN14
Gene Name calpain 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000214711
Encoded Proteins
calpain 14
calpain 14
calpain 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:31173056-31233858
Strand Reverse strand
Band p23.1
Transcripts
ENST00000398824 ENSP00000381805
ENST00000403897 ENSP00000385247
ENST00000444918 ENSP00000398670
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.468059
RefSeq NM_001145122 XM_006712022
HUGO
OMIM
CCDS CCDS46254
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas