Version 5.4
Homo sapiens Protein: CAPN14
Summary
InnateDB Protein IDBP-294224.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPN14
Protein Name calpain 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000385247
InnateDB Gene IDBG-232114 (CAPN14)
Protein Structure
UniProt Annotation
Function Calcium-regulated non-lysosomal thiol-protease. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Not expressed in tissues tested.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001300 Peptidase C2, calpain, catalytic domain
IPR002048 EF-hand domain
IPR022682 Peptidase C2, calpain, large subunit, domain III
IPR022683 Peptidase C2, calpain, domain III
IPR022684 Peptidase C2, calpain family
PFAM PF00648
PF00036
PF13202
PF13405
PF01067
PRINTS PR00704
PIRSF
SMART SM00230
SM00054
SM00720
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A8MX76
PhosphoSite PhosphoSite-BAG52511
TrEMBL
UniProt Splice Variant
Entrez Gene 440854
UniGene Hs.468059
RefSeq NP_001138594
HUGO HGNC:16664
OMIM 610229
CCDS CCDS46254
HPRD
IMGT
EMBL AC015980 AK092257
GenPept BAG52511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca