Version 5.4
Homo sapiens Gene: LTB4R2
Summary
InnateDB Gene IDBG-236766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LTB4R2
Gene Name leukotriene B4 receptor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213906
Encoded Proteins
IDBP-586832
leukotriene B4 receptor 2
IDBP-589178
leukotriene B4 receptor 2
IDBP-592783
leukotriene B4 receptor 2
IDBP-586892
leukotriene B4 receptor 2
IDBP-583593
leukotriene B4 receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:24305734-24312053
Strand Forward strand
Band q12
Transcripts
ENST00000527924 ENSP00000436668
ENST00000528054 ENSP00000432146
ENST00000533293 ENSP00000433290
ENST00000530080 ENSP00000434760
ENST00000543919 ENSP00000445772
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001632 leukotriene B4 receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004974 leukotriene receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007194 negative regulation of adenylate cyclase activity
GO:0051546 keratinocyte migration
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040432
View Gene Order
ENSBTAG00000040056
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_18302
Leukotriene receptors pathway
REACT_18352
Eicosanoid ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
hsa04020
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9NPC1
TrEMBL E9PIC1 E9PNJ6
UniProt Splice Variant
Entrez Gene 56413
UniGene Hs.657595
RefSeq NM_001164692 NM_019839
HUGO HGNC:19260
OMIM 605773
CCDS CCDS9625
HPRD 16153
IMGT
EMBL AB008193 AB029892 AB032558 AB044402 AB083604 AF277230 AF308571 AJ278605 AL096870 AY268433 CH471078
GenPept AAF81261 AAG40857 AAP23200 BAA99539 BAA99553 BAB00610 BAB89317 BAD83590 CAB96134 EAW66030
RNA Seq Atlas 56413

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca