InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LTB4R2

Summary

InnateDB Protein

IDBP-592783.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LTB4R2

Protein Name

leukotriene B4 receptor 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000433290

InnateDB Gene

IDBG-236766 (LTB4R2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004974	leukotriene receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007194	negative regulation of adenylate cyclase activity

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR003981 Leukotriene B4 receptor
IPR003982 Leukotriene B4 type 2 receptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01476
PR01478

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NPC1

PhosphoSite

PhosphoSite-Q9NPC1

TrEMBL

E9PNJ6

UniProt Splice Variant

Entrez Gene

56413

UniGene

Hs.657595

RefSeq

HUGO

HGNC:19260

OMIM

605773

CCDS

CCDS9625

HPRD

16153

IMGT

EMBL

AB008193 AB029892 AB032558 AB044402 AB083604 AF277230 AF308571 AJ278605 AL096870 AY268433 CH471078

GenPept

AAF81261 AAG40857 AAP23200 BAA99539 BAA99553 BAB00610 BAB89317 BAD83590 CAB96134 EAW66030