Version 5.4
Homo sapiens Gene: G3BP2
Summary
InnateDB Gene IDBG-24688.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G3BP2
Gene Name GTPase activating protein (SH3 domain) binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138757
Encoded Proteins
IDBP-24690
GTPase activating protein (SH3 domain) binding protein 2
IDBP-24692
GTPase activating protein (SH3 domain) binding protein 2
IDBP-238974
GTPase activating protein (SH3 domain) binding protein 2
IDBP-483804
GTPase activating protein (SH3 domain) binding protein 2
IDBP-485417
GTPase activating protein (SH3 domain) binding protein 2
IDBP-479742
GTPase activating protein (SH3 domain) binding protein 2
IDBP-479405
GTPase activating protein (SH3 domain) binding protein 2
IDBP-481500
GTPase activating protein (SH3 domain) binding protein 2
IDBP-476977
GTPase activating protein (SH3 domain) binding protein 2
IDBP-477603
GTPase activating protein (SH3 domain) binding protein 2
IDBP-473726
GTPase activating protein (SH3 domain) binding protein 2
IDBP-480179
GTPase activating protein (SH3 domain) binding protein 2
IDBP-478843
GTPase activating protein (SH3 domain) binding protein 2
IDBP-485416
GTPase activating protein (SH3 domain) binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:75642782-75724525
Strand Reverse strand
Band q21.1
Transcripts
ENST00000359707 ENSP00000352738
ENST00000357854 ENSP00000350518
ENST00000395719 ENSP00000379069
ENST00000507133
ENST00000507947
ENST00000510902 ENSP00000426843
ENST00000503660 ENSP00000424522
ENST00000502654
ENST00000507745 ENSP00000422748
ENST00000513927
ENST00000509100 ENSP00000426311
ENST00000511146 ENSP00000423960
ENST00000515457 ENSP00000425122
ENST00000507252 ENSP00000422614
ENST00000511868 ENSP00000421621
ENST00000509561 ENSP00000424060
ENST00000508510 ENSP00000423245
ENST00000499709 ENSP00000422830
ENST00000507701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 53 [view]
Protein-Protein 50 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0030159 receptor signaling complex scaffold activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006810 transport
GO:0007253 cytoplasmic sequestering of NF-kappaB
GO:0007265 Ras protein signal transduction
GO:0051028 mRNA transport
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029405
View Gene Order
ENSBTAG00000014041
Not yet available
Pathways
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.303676 Hs.651766 Hs.705535
RefSeq NM_012297 NM_203504 NM_203505 XM_005263382 XM_005263383 XM_005263384 XM_005263385 XM_005263386
HUGO
OMIM
CCDS CCDS3571 CCDS3572
HPRD 06570
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca