Version 5.4
Homo sapiens Gene: SHROOM3
Summary
InnateDB Gene IDBG-25553.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHROOM3
Gene Name shroom family member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138771
Encoded Proteins
IDBP-25559
shroom family member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:76435100-76783253
Strand Forward strand
Band q21.1
Transcripts
ENST00000296043 ENSP00000296043
ENST00000497440
ENST00000466541
ENST00000469923
ENST00000490690
ENST00000481002
ENST00000485780
ENST00000484236
ENST00000486758
ENST00000473602
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0000902 cell morphogenesis
GO:0001843 neural tube closure
GO:0002066 columnar/cuboidal epithelial cell development
GO:0007389 pattern specification process
GO:0008360 regulation of cell shape
GO:0030036 actin cytoskeleton organization
GO:0043482 cellular pigment accumulation
GO:0045176 apical protein localization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005912 adherens junction
GO:0016324 apical plasma membrane
GO:0043296 apical junction complex
GO:0045177 apical part of cell
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029381
View Gene Order
ENSBTAG00000019633
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.432504 Hs.606207 Hs.683808 Hs.689676 Hs.702168
RefSeq NM_020859 XM_005263162 XM_005263163 XM_005263164 XM_005263165 XM_006714282
HUGO
OMIM
CCDS CCDS3579
HPRD 07053
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca