InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ccrl1

Summary

InnateDB Gene

IDBG-255670.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccrl1

Gene Name

chemokine (C-C motif) receptor-like 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000079355

Encoded Proteins

IDBP-194851

chemokine (C-C motif) receptor-like 1

IDBP-787766

atypical chemokine receptor 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129048:
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:104084157-104126933

Strand

Reverse strand

Band

Transcripts

ENSMUST00000076147	ENSMUSP00000075507
ENSMUST00000188000	ENSMUSP00000140792

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004950	chemokine receptor activity
GO:0005044	scavenger receptor activity
GO:0005515	protein binding
GO:0019956	chemokine binding

Biological Process

GO:0006898	receptor-mediated endocytosis
GO:0006935	chemotaxis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0070098	chemokine-mediated signaling pathway