Mus musculus Gene: Ccrl1
Summary
InnateDB Gene IDBG-255670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccrl1
Gene Name chemokine (C-C motif) receptor-like 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000079355
Encoded Proteins
chemokine (C-C motif) receptor-like 1
atypical chemokine receptor 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129048:
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:104084157-104126933
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000076147 ENSMUSP00000075507
ENSMUST00000188000 ENSMUSP00000140792
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0019956 chemokine binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Peptide ligand-binding receptors pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
Chemokine receptors bind chemokines pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 252837
UniGene
RefSeq XM_006511734 NM_145700
OMIM
CCDS CCDS23459
HPRD
IMGT
MGI ID MGI:2181676
MGI Symbol Ackr4
EMBL AF306532 AK030643 AK042430 AY072796 AY072938
GenPept AAK81712 AAL68400 AAL68962 BAC27061 BAC31258
RNA Seq Atlas 252837