Version 5.4
Homo sapiens Gene: HNF4G
Summary
InnateDB Gene IDBG-25986.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNF4G
Gene Name hepatocyte nuclear factor 4, gamma
Synonyms NR2A2; NR2A3
Species Homo sapiens
Ensembl Gene ENSG00000164749
Encoded Proteins
IDBP-25988
hepatocyte nuclear factor 4, gamma
IDBP-237544
hepatocyte nuclear factor 4, gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:75407914-75566843
Strand Forward strand
Band q21.13
Transcripts
ENST00000354370 ENSP00000346339
ENST00000396423 ENSP00000379701
ENST00000396419
ENST00000494318
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0010467 gene expression
GO:0030522 intracellular receptor signaling pathway
GO:0031018 endocrine pancreas development
GO:0043401 steroid hormone mediated signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017688
View Gene Order
ENSBTAG00000008280
Not yet available
Pathways
NETPATH
REACTOME
REACT_15525
Nuclear Receptor transcription pathway pathway
REACT_12627
Generic Transcription Pathway pathway
REACT_13819
Regulation of gene expression in beta cells pathway
REACT_111045
Developmental Biology pathway
REACT_13698
Regulation of beta-cell development pathway
REACT_71
Gene Expression pathway
KEGG
hsa04950
Maturity onset diabetes of the young pathway
INOH
PID NCI
Cross-References
SwissProt Q14541
TrEMBL F1D8Q4
UniProt Splice Variant
Entrez Gene 3174
UniGene Hs.241529 Hs.734080
RefSeq NM_004133 XM_006716446
HUGO HGNC:5026
OMIM 605966
CCDS CCDS6220
HPRD
IMGT
EMBL AF133496 AF133497 AF133498 AF133499 AF133500 AF133501 AF133502 AF133503 AF133504 AF207953 BC105009 BC105011 BX571750 HQ692842 Z49826
GenPept AAF00110 AAI05010 AAI05012 ADZ17353 CAA89990 CAE11875
RNA Seq Atlas 3174

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca