Version 5.4
Homo sapiens Gene: MEX3B
Summary
InnateDB Gene IDBG-26170.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEX3B
Gene Name mex-3 homolog B (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183496
Encoded Proteins
IDBP-26172
mex-3 homolog B (C. elegans)
IDBP-744952
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:82041778-82046141
Strand Reverse strand
Band q25.2
Transcripts
ENST00000329713 ENSP00000329918
ENST00000558133 ENSP00000456938
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 3 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006468 protein phosphorylation
GO:0046777 protein autophosphorylation
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000057706
View Gene Order
ENSBTAG00000016630
Not yet available
Cross-References
SwissProt Q6ZN04
TrEMBL
UniProt Splice Variant
Entrez Gene 84206
UniGene Hs.104744
RefSeq NM_032246
HUGO HGNC:25297
OMIM 611008
CCDS CCDS10319
HPRD 15256
IMGT
EMBL AB095929 AK131424 AL136778 AY950678 BC036211 BC111545
GenPept AAH36211 AAI11546 AAY34146 BAC23105 BAD18571 CAB66712
RNA Seq Atlas 84206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca