Homo sapiens Gene: FHOD3
Summary
InnateDB Gene IDBG-2618.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FHOD3
Gene Name formin homology 2 domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134775
Encoded Proteins
formin homology 2 domain containing 3
formin homology 2 domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Proteins that contain formin (FMN1; MIM 136535) homology (FH) domains, such as FHOD3, play a role in regulation of the actin cytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:36297714-36780055
Strand Forward strand
Band q12.2
Transcripts
ENST00000359247 ENSP00000352186
ENST00000257209 ENSP00000257209
ENST00000585579 ENSP00000465843
ENST00000591635 ENSP00000467195
ENST00000592930 ENSP00000468163
ENST00000589114
ENST00000590592 ENSP00000466937
ENST00000587493
ENST00000592128 ENSP00000467462
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007015 actin filament organization
GO:0030837 negative regulation of actin filament polymerization
GO:0045214 sarcomere organization
GO:0051639 actin filament network formation
GO:0055003 cardiac myofibril assembly
Cellular Component
GO:0005865 striated muscle thin filament
GO:0030017 sarcomere
GO:0030018 Z disc
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL K7EP24
UniProt Splice Variant
Entrez Gene 80206
UniGene Hs.630884
RefSeq NM_001281739 NM_001281740 NM_025135 XM_005258346 XM_005258350 XM_005258355
HUGO HGNC:26178
OMIM 609691
CCDS CCDS32816 CCDS62418 CCDS62419
HPRD 16894
IMGT
EMBL AC023043 AC055840 AC090333 AC131053
GenPept
RNA Seq Atlas 80206