Version 5.4
Homo sapiens Gene: FHOD3
Summary
InnateDB Gene IDBG-2618.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FHOD3
Gene Name formin homology 2 domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134775
Encoded Proteins
IDBP-2620
formin homology 2 domain containing 3
IDBP-2622
formin homology 2 domain containing 3
IDBP-725713
IDBP-726640
IDBP-725948
IDBP-727573
IDBP-726703
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Proteins that contain formin (FMN1; MIM 136535) homology (FH) domains, such as FHOD3, play a role in regulation of the actin cytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:36297714-36780055
Strand Forward strand
Band q12.2
Transcripts
ENST00000359247 ENSP00000352186
ENST00000257209 ENSP00000257209
ENST00000585579 ENSP00000465843
ENST00000591635 ENSP00000467195
ENST00000592930 ENSP00000468163
ENST00000589114
ENST00000590592 ENSP00000466937
ENST00000587493
ENST00000592128 ENSP00000467462
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007015 actin filament organization
GO:0030837 negative regulation of actin filament polymerization
GO:0045214 sarcomere organization
GO:0051639 actin filament network formation
GO:0055003 cardiac myofibril assembly
Cellular Component
GO:0005865 striated muscle thin filament
GO:0030017 sarcomere
GO:0030018 Z disc
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034295
View Gene Order
ENSBTAG00000021581
Not yet available
Cross-References
SwissProt Q2V2M9
TrEMBL
UniProt Splice Variant
Entrez Gene 80206
UniGene Hs.630884
RefSeq NM_001281739 NM_001281740 NM_025135 XM_005258346 XM_005258350 XM_005258355
HUGO HGNC:26178
OMIM 609691
CCDS CCDS32816 CCDS62418 CCDS62419
HPRD 16894
IMGT
EMBL AB051482 AB084087 AC023043 AC055840 AC090333 AC131053 AK025950 AK026370 AK128053 AL834480 BC050670 BC081563 HM191478
GenPept AAH50670 AAH81563 ADL62709 BAB15292 BAB15463 BAB21786 BAC67014 BAC87252 CAD39139
RNA Seq Atlas 80206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca