Homo sapiens Gene: CELF4
Summary
InnateDB Gene IDBG-2659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CELF4
Gene Name CUGBP, Elav-like family member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101489
Encoded Proteins
CUGBP, Elav-like family member 4
CUGBP, Elav-like family member 4
CUGBP, Elav-like family member 4
CUGBP, Elav-like family member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37243047-37566037
Strand Reverse strand
Band q12.2
Transcripts
ENST00000361795 ENSP00000355089
ENST00000334919 ENSP00000335631
ENST00000420428 ENSP00000410584
ENST00000588597 ENSP00000468109
ENST00000591421
ENST00000591282 ENSP00000464794
ENST00000587911 ENSP00000471616
ENST00000591287 ENSP00000464917
ENST00000589386 ENSP00000465125
ENST00000593271 ENSP00000464996
ENST00000589229 ENSP00000465211
ENST00000586009 ENSP00000465348
ENST00000587074
ENST00000601019 ENSP00000469627
ENST00000587449
ENST00000588591 ENSP00000468256
ENST00000590011
ENST00000601392 ENSP00000470649
ENST00000590112 ENSP00000468428
ENST00000587657 ENSP00000467056
ENST00000587819 ENSP00000467732
ENST00000587924 ENSP00000467571
ENST00000603232 ENSP00000474788
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000900 translation repressor activity, nucleic acid binding
GO:0003676 nucleic acid binding
GO:0003729 mRNA binding
GO:0042835 BRE binding
Biological Process
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006376 mRNA splice site selection
GO:0007281 germ cell development
GO:0009790 embryo development
GO:0017148 negative regulation of translation
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0090394 negative regulation of excitatory postsynaptic membrane potential
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL K7EQ97
UniProt Splice Variant
Entrez Gene 56853
UniGene Hs.435976 Hs.600908 Hs.602283
RefSeq NM_001025088 NM_001025089 NM_020180 NM_001025087 XM_006722509 XM_005258308
HUGO HGNC:14015
OMIM 612679
CCDS CCDS32818 CCDS45857 CCDS45858
HPRD 12534
IMGT
EMBL AC015961 AC090386 AC093332 AC129908
GenPept
RNA Seq Atlas 56853