Version 5.4
| Homo sapiens Gene: GNG11 | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-27227.5 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | GNG11 | ||||||||||||||||||
| Gene Name | guanine nucleotide binding protein (G protein), gamma 11 | ||||||||||||||||||
| Synonyms | GNGT11 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000127920 | ||||||||||||||||||
| Encoded Proteins |
guanine nucleotide binding protein (G protein), gamma 11
|
||||||||||||||||||
| Protein Structure |
|
||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008] |
||||||||||||||||||
| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 7:93921699-93928610 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q21.3 | ||||||||||||||||||
| Transcripts |
|
||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
| Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
| Biological Process |
|
||||||||||||||||||
| Cellular Component |
|
||||||||||||||||||
| Orthologs | |||||||||||||||||||
|
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Prostacyclin signalling through prostacyclin receptor pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 12 pathway
ADP signalling through P2Y purinoceptor 1 pathway
Thromboxane signalling through TP receptor pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (i) signalling events pathway
G beta:gamma signalling through PI3Kgamma pathway
G beta:gamma signalling through PLC beta pathway
G alpha (12/13) signalling events pathway
G alpha (s) signalling events pathway
G alpha (z) signalling events pathway
Glucagon-type ligand receptors pathway
Class B/2 (Secretin family receptors) pathway
G-protein activation pathway
Opioid Signalling pathway
Presynaptic function of Kainate receptors pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Regulation of insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Activation of Kainate Receptors upon glutamate binding pathway
Transmission across Chemical Synapses pathway
GPCR ligand binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Signal amplification pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
|
||||||||||||||||||
| KEGG |
Chemokine signaling pathway pathway
|
||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | P61952 | ||||||||||||||||||
| TrEMBL | Q53Y01 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 2791 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_004126 | ||||||||||||||||||
| HUGO | HGNC:4403 | ||||||||||||||||||
| OMIM | 604390 | ||||||||||||||||||
| CCDS | CCDS5634 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC002076 AF493878 AK312037 BC009709 BT007141 CH236949 CH471091 U31384 | ||||||||||||||||||
| GenPept | AAC50206 AAH09709 AAM12592 AAP35805 AAS02020 BAG34974 EAL24138 EAW76804 | ||||||||||||||||||
| RNA Seq Atlas | 2791 | ||||||||||||||||||