InnateDB Protein
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IDBP-27229.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GNG11
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Protein Name
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guanine nucleotide binding protein (G protein), gamma 11
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Synonyms
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GNGT11;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000248564
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InnateDB Gene
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IDBG-27227 (GNG11)
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Protein Structure
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Abundantly expressed in all tissues tested except for brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001770
G-protein, gamma subunit
IPR015898
G-protein gamma-like domain
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PFAM |
PF00631
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PRINTS |
PR00321
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PIRSF |
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SMART |
SM00224
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TIGRFAMs |
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Modification |
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SwissProt |
P61952
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PhosphoSite |
PhosphoSite-P61952
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TrEMBL |
Q53Y01
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UniProt Splice Variant |
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Entrez Gene |
2791
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UniGene |
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RefSeq |
NP_004117
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HUGO |
HGNC:4403
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OMIM |
604390
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CCDS |
CCDS5634
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HPRD |
11979
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IMGT |
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EMBL |
AC002076
AF493878
AK312037
BC009709
BT007141
CH236949
CH471091
U31384
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GenPept |
AAC50206
AAH09709
AAM12592
AAP35805
AAS02020
BAG34974
EAL24138
EAW76804
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