Homo sapiens Gene: BDP1
Summary
InnateDB Gene IDBG-27250.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BDP1
Gene Name B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145734
Encoded Proteins
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:71455615-71567820
Strand Forward strand
Band q13.2
Transcripts
ENST00000358731 ENSP00000351575
ENST00000380675 ENSP00000370050
ENST00000508917
ENST00000508157
ENST00000514903 ENSP00000421910
ENST00000525844 ENSP00000432404
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0010467 gene expression
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase III Transcription pathway
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
KEGG
INOH
PID BIOCARTA
Rna polymerase iii transcription [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.258272
RefSeq NM_018429 XM_005276771 XM_006714658 XM_006714659 XM_006725460 XM_006725461 XM_006726216
HUGO
OMIM
CCDS CCDS43328
HPRD 06114
IMGT
EMBL
GenPept
RNA Seq Atlas