Version 5.4
Homo sapiens Gene: CNTROB
Summary
InnateDB Gene IDBG-27418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNTROB
Gene Name centrobin, centrosomal BRCA2 interacting protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170037
Encoded Proteins
IDBP-27420
centrobin, centrosomal BRCA2 interacting protein
IDBP-764706
IDBP-759864
IDBP-759176
IDBP-759347
IDBP-762322
IDBP-758542
IDBP-760958
IDBP-761389
IDBP-762974
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:7932101-7949918
Strand Forward strand
Band p13.1
Transcripts
ENST00000380262 ENSP00000369614
ENST00000570782 ENSP00000460583
ENST00000576723
ENST00000570784 ENSP00000461000
ENST00000563694 ENSP00000456335
ENST00000576922
ENST00000571632 ENSP00000458787
ENST00000573862
ENST00000576536 ENSP00000458251
ENST00000565740 ENSP00000454840
ENST00000576538 ENSP00000459246
ENST00000571540 ENSP00000458688
ENST00000575408 ENSP00000458696
ENST00000576587
ENST00000574430
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0000910 cytokinesis
GO:0007099 centriole replication
GO:0051299 centrosome separation
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032782
View Gene Order
ENSBTAG00000047756
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.348012 Hs.732863
RefSeq NM_001037144 NM_053051 XM_005256437 XM_005256438 XM_005256439 XM_006721438 XM_006721440
HUGO
OMIM
CCDS CCDS11126 CCDS32557
HPRD 13991
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca