Version 5.4
Homo sapiens Gene: NMB
Summary
InnateDB Gene IDBG-27675.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMB
Gene Name neuromedin B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000197696
Encoded Proteins
IDBP-27677
neuromedin B
IDBP-241296
neuromedin B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:84655129-84658563
Strand Reverse strand
Band q25.2
Transcripts
ENST00000360476 ENSP00000353664
ENST00000394588 ENSP00000378089
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0031710 neuromedin B receptor binding
Biological Process
GO:0007165 signal transduction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007267 cell-cell signaling
GO:0008284 positive regulation of cell proliferation
GO:0042593 glucose homeostasis
GO:0046887 positive regulation of hormone secretion
GO:0046888 negative regulation of hormone secretion
GO:0050482 arachidonic acid secretion
Cellular Component
GO:0005576 extracellular region
GO:0043005 neuron projection
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025723
View Gene Order
ENSBTAG00000001388
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P08949
TrEMBL
UniProt Splice Variant
Entrez Gene 4828
UniGene Hs.386470
RefSeq NM_205858 NM_021077
HUGO HGNC:7842
OMIM 162340
CCDS CCDS42076 CCDS10332
HPRD 01210
IMGT
EMBL AC048382 BC007407 BC007431 BC008603 M21551
GenPept AAA59934 AAH07407 AAH07431 AAH08603
RNA Seq Atlas 4828

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca