Version 5.4
Homo sapiens Gene: HELQ
Summary
InnateDB Gene IDBG-27742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HELQ
Gene Name helicase, POLQ-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163312
Encoded Proteins
IDBP-27744
helicase, POLQ-like
IDBP-482012
helicase, POLQ-like
IDBP-475418
helicase, POLQ-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 [PubMed 11751861]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:83407343-83455856
Strand Reverse strand
Band q21.23
Transcripts
ENST00000295488 ENSP00000295488
ENST00000440639
ENST00000508591 ENSP00000424186
ENST00000512539
ENST00000510985 ENSP00000424539
ENST00000515482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000035266
View Gene Order
Cross-References
SwissProt Q8TDG4
TrEMBL
UniProt Splice Variant
Entrez Gene 113510
UniGene Hs.480101
RefSeq NM_001297756 NM_133636 XM_005262711 XM_005262714 XM_006714076 NM_001297755 NM_001297757 XM_005262712
HUGO HGNC:18536
OMIM 606769
CCDS CCDS3603 CCDS75158
HPRD 08422
IMGT
EMBL AC096768 AF436845 AK128665 AL512702 BC015428 BC095473
GenPept AAH15428 AAH95473 AAL85274 BAC87559 CAH56359
RNA Seq Atlas 113510

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca