Version 5.4
Homo sapiens Protein: HELQ
Summary
InnateDB Protein IDBP-475418.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HELQ
Protein Name helicase, POLQ-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000424539
InnateDB Gene IDBG-27742 (HELQ)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR001650 Helicase, C-terminal
IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00271
PRINTS
PIRSF
SMART SM00490
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E3W980
UniProt Splice Variant
Entrez Gene 113510
UniGene Hs.480101
RefSeq NP_001284688
HUGO HGNC:18536
OMIM 606769
CCDS CCDS75158
HPRD 08422
IMGT
EMBL AC096768
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca