Version 5.4
Homo sapiens Gene: AGPAT9
Summary
InnateDB Gene IDBG-27850.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGPAT9
Gene Name 1-acylglycerol-3-phosphate O-acyltransferase 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138678
Encoded Proteins
IDBP-27852
1-acylglycerol-3-phosphate O-acyltransferase 9
IDBP-239996
1-acylglycerol-3-phosphate O-acyltransferase 9
IDBP-809313
1-acylglycerol-3-phosphate O-acyltransferase 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:83535914-83605875
Strand Forward strand
Band q21.23
Transcripts
ENST00000264409 ENSP00000264409
ENST00000395226 ENSP00000378651
ENST00000514309
ENST00000506766
ENST00000509412
ENST00000513683
ENST00000509044
ENST00000611707 ENSP00000482571
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0004366 glycerol-3-phosphate O-acyltransferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0008152 metabolic process
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0032006 regulation of TOR signaling
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029314
View Gene Order
ENSBTAG00000017592
Not yet available
Pathways
NETPATH
REACTOME
REACT_120906
Synthesis of PA pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.739239 Hs.99196
RefSeq NM_001256421 NM_001256422 NM_032717 XM_005263314
HUGO
OMIM
CCDS CCDS3606
HPRD 14417
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca