Version 5.4
Homo sapiens Gene: KRTAP1-3
Summary
InnateDB Gene IDBG-281648.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRTAP1-3
Gene Name keratin associated protein 1-3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000221880
Encoded Proteins
IDBP-48598
keratin associated protein 1-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41033884-41034855
Strand Reverse strand
Band q21.2
Transcripts
ENST00000344363 ENSP00000344420
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030280 structural constituent of epidermis
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0045095 keratin filament
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8IUG1
TrEMBL
UniProt Splice Variant
Entrez Gene 81850
UniGene Hs.534495
RefSeq NM_030966
HUGO HGNC:16771
OMIM 608820
CCDS CCDS42323
HPRD
IMGT
EMBL AB081338 AB081339 AJ406927 BC069161 BC101150 BC101151 BC101152 BC101153 X63338
GenPept AAH69161 AAI01151 AAI01152 AAI01153 AAI01154 BAC15619 BAC15620 CAA44938 CAC27566
RNA Seq Atlas 81850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca