Version 5.4
Homo sapiens Gene: AFF1
Summary
InnateDB Gene IDBG-28741.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AFF1
Gene Name AF4/FMR2 family, member 1
Synonyms AF4; MLLT2; PBM1
Species Homo sapiens
Ensembl Gene ENSG00000172493
Encoded Proteins
IDBP-28745
AF4/FMR2 family, member 1
IDBP-240144
AF4/FMR2 family, member 1
IDBP-484759
AF4/FMR2 family, member 1
IDBP-481158
AF4/FMR2 family, member 1
IDBP-484501
AF4/FMR2 family, member 1
IDBP-480717
AF4/FMR2 family, member 1
IDBP-478651
AF4/FMR2 family, member 1
IDBP-601889
AF4/FMR2 family, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:86935002-87141054
Strand Forward strand
Band q21.3
Transcripts
ENST00000307808 ENSP00000305689
ENST00000395146 ENSP00000378578
ENST00000504956
ENST00000507468 ENSP00000427593
ENST00000503477 ENSP00000424483
ENST00000511996
ENST00000511442 ENSP00000425755
ENST00000511722 ENSP00000424766
ENST00000514970 ENSP00000424881
ENST00000503369
ENST00000544085 ENSP00000440843
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029313
View Gene Order
ENSBTAG00000018488
Not yet available
Cross-References
SwissProt
TrEMBL B4DXZ8 D6RIZ5 E7EMC5
UniProt Splice Variant
Entrez Gene 4299
UniGene Hs.480190 Hs.595318 Hs.607658
RefSeq NM_001166693 NM_005935 XM_005263007 XM_005263008 XM_005263009 XM_005263010 XM_005263011 XM_005263012
HUGO HGNC:7135
OMIM 159557
CCDS CCDS3616 CCDS54775
HPRD 08871
IMGT
EMBL AC092658 AC093779 AC093827 AK302199
GenPept BAG63560
RNA Seq Atlas 4299

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca