Version 5.4
Homo sapiens Protein: AFF1
Summary
InnateDB Protein IDBP-240144.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AFF1
Protein Name AF4/FMR2 family, member 1
Synonyms AF4; MLLT2; PBM1;
Species Homo sapiens
Ensembl Protein ENSP00000378578
InnateDB Gene IDBG-28741 (AFF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007797 Transcription factor AF4/FMR2
PFAM PF05110
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51825
PhosphoSite PhosphoSite-P51825
TrEMBL Q712L1
UniProt Splice Variant
Entrez Gene 4299
UniGene Hs.607658
RefSeq NP_001160165
HUGO HGNC:7135
OMIM 159557
CCDS CCDS54775
HPRD 08871
IMGT
EMBL AC092658 AC093779 AC093827 AJ238093 AK300364 L13773 L25050
GenPept AAA36642 AAA58360 AAY40899 BAG62103 CAB52416

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca