InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SNRPD3

Summary

InnateDB Gene

IDBG-2890.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNRPD3

Gene Name

small nuclear ribonucleoprotein D3 polypeptide 18kDa

Synonyms

Sm-D3; SMD3

Species

Homo sapiens

Ensembl Gene

ENSG00000100028

Encoded Proteins

IDBP-2892

small nuclear ribonucleoprotein D3 polypeptide 18kDa

IDBP-295017

small nuclear ribonucleoprotein D3 polypeptide 18kDa

IDBP-719930

IDBP-719799

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. [provided by RefSeq, Jul 2008]
This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:24555503-24609980

Strand

Forward strand

Band

q11.23

Transcripts

ENST00000215829	ENSP00000215829
ENST00000402849	ENSP00000385266
ENST00000404603	ENSP00000456090
ENST00000439775	ENSP00000456969
ENST00000468770

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 117 experimentally validated interaction(s) in this database.

Experimentally validated
Total	117 [view]
Protein-Protein	113 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0044822	poly(A) RNA binding
GO:0071208	histone pre-mRNA DCP binding

Biological Process

GO:0000387	spliceosomal snRNP assembly
GO:0000398	mRNA splicing, via spliceosome
GO:0006366	transcription from RNA polymerase II promoter
GO:0006369	termination of RNA polymerase II transcription
GO:0008334	histone mRNA metabolic process
GO:0008380	RNA splicing
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0031124	mRNA 3'-end processing
GO:0034660	ncRNA metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005683	U7 snRNP
GO:0005685	U1 snRNP
GO:0005687	U4 snRNP
GO:0005689	U12-type spliceosomal complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0019013	viral nucleocapsid
GO:0030529	ribonucleoprotein complex
GO:0030532	small nuclear ribonucleoprotein complex
GO:0034709	methylosome
GO:0034715	pICln-Sm protein complex
GO:0034719	SMN-Sm protein complex
GO:0070062	extracellular vesicular exosome
GO:0071013	catalytic step 2 spliceosome