Homo sapiens Gene: SNRPD3
Summary
InnateDB Gene IDBG-2890.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNRPD3
Gene Name small nuclear ribonucleoprotein D3 polypeptide 18kDa
Synonyms Sm-D3; SMD3;
Species Homo sapiens
Ensembl Gene ENSG00000100028
Encoded Proteins
small nuclear ribonucleoprotein D3 polypeptide 18kDa
small nuclear ribonucleoprotein D3 polypeptide 18kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. [provided by RefSeq, Jul 2008]
This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:24555503-24609980
Strand Forward strand
Band q11.23
Transcripts
ENST00000215829 ENSP00000215829
ENST00000402849 ENSP00000385266
ENST00000404603 ENSP00000456090
ENST00000439775 ENSP00000456969
ENST00000468770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 117 experimentally validated interaction(s) in this database.
Experimentally validated
Total 117 [view]
Protein-Protein 113 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0044822 poly(A) RNA binding
GO:0071208 histone pre-mRNA DCP binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0008334 histone mRNA metabolic process
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0031124 mRNA 3'-end processing
GO:0034660 ncRNA metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005683 U7 snRNP
GO:0005685 U1 snRNP
GO:0005687 U4 snRNP
GO:0005689 U12-type spliceosomal complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0019013 viral nucleocapsid
GO:0030529 ribonucleoprotein complex
GO:0030532 small nuclear ribonucleoprotein complex
GO:0034709 methylosome
GO:0034715 pICln-Sm protein complex
GO:0034719 SMN-Sm protein complex
GO:0070062 extracellular vesicular exosome
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
SLBP independent Processing of Histone Pre-mRNAs pathway
RNA Polymerase II Transcription Termination pathway
mRNA Splicing - Minor Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs pathway
RNA Polymerase II Transcription pathway
Metabolism of non-coding RNA pathway
Processing of Capped Intronless Pre-mRNA pathway
mRNA Splicing pathway
Cleavage of Growing Transcript in the Termination Region pathway
snRNP Assembly pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
Spliceosome pathway
Systemic lupus erythematosus pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL B4DJP7
UniProt Splice Variant
Entrez Gene 6634
UniGene Hs.356549
RefSeq NM_001278656 NM_004175
HUGO HGNC:11160
OMIM 601062
CCDS CCDS13828
HPRD 03039
IMGT
EMBL AK296173 AP000356
GenPept BAG58909
RNA Seq Atlas 6634