Homo sapiens Gene: RPL26
Summary
InnateDB Gene IDBG-28900.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPL26
Gene Name ribosomal protein L26
Synonyms DBA11; L26
Species Homo sapiens
Ensembl Gene ENSG00000161970
Encoded Proteins
ribosomal protein L26
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:8377520-8383213
Strand Reverse strand
Band p13.1
Transcripts
ENST00000293842 ENSP00000293842
ENST00000582485 ENSP00000464143
ENST00000584343 ENSP00000464239
ENST00000584441 ENSP00000462249
ENST00000578069
ENST00000583515 ENSP00000463021
ENST00000578115
ENST00000582556 ENSP00000463470
ENST00000584164 ENSP00000463784
ENST00000585176
ENST00000578812 ENSP00000463910
ENST00000583011 ENSP00000462322
ENST00000584906 ENSP00000462619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
Experimentally validated
Total 62 [view]
Protein-Protein 61 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0042273 ribosomal large subunit biogenesis
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005829 cytosol
GO:0015934 large ribosomal subunit
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of a pool of free 40S subunits pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL J3KS10
UniProt Splice Variant
Entrez Gene 6154
UniGene Hs.482144 Hs.633688
RefSeq NM_000987 XM_005256749 XM_005256750
HUGO HGNC:10327
OMIM 603704
CCDS CCDS11142
HPRD 04746
IMGT
EMBL AC135178
GenPept
RNA Seq Atlas 6154