InnateDB Protein
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IDBP-28902.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RPL26
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Protein Name
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ribosomal protein L26
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Synonyms
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DBA11; L26;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000293842
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InnateDB Gene
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IDBG-28900 (RPL26)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
Diamond-Blackfan anemia 11 (DBA11) [MIM:614900]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. {ECO:0000269PubMed:22431104}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
62
[view]
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Protein-Protein |
61
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR005756
Ribosomal protein L26/L24P, eukaryotic/archaeal
IPR005824
KOW
IPR008991
Translation protein SH3-like domain
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PFAM |
PF00467
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PRINTS |
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PIRSF |
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SMART |
SM00739
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TIGRFAMs |
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Modification |
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SwissProt |
P61254
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PhosphoSite |
PhosphoSite-P61254
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TrEMBL |
J3QRI7
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UniProt Splice Variant |
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Entrez Gene |
6154
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UniGene |
Hs.633688
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RefSeq |
NP_000978
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HUGO |
HGNC:10327
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OMIM |
603704
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CCDS |
CCDS11142
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HPRD |
04746
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IMGT |
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EMBL |
AB061829
AC135178
AK311804
BC071664
CH471108
L07287
X69392
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GenPept |
AAA60279
AAH71664
BAB79467
BAG34747
CAA49189
EAW90053
EAW90054
EAW90057
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