Version 5.4
Homo sapiens Gene: KANK2
Summary
InnateDB Gene IDBG-28941.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KANK2
Gene Name KN motif and ankyrin repeat domains 2
Synonyms ANKRD25; MXRA3; SIP
Species Homo sapiens
Ensembl Gene ENSG00000197256
Encoded Proteins
IDBP-762379
IDBP-766208
IDBP-763781
IDBP-761390
IDBP-760498
IDBP-765968
IDBP-765474
IDBP-760606
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11164267-11197791
Strand Reverse strand
Band p13.2
Transcripts
ENST00000590095
ENST00000588724 ENSP00000465914
ENST00000592903 ENSP00000464861
ENST00000592675 ENSP00000468409
ENST00000589427
ENST00000592215
ENST00000589894 ENSP00000467029
ENST00000586659 ENSP00000465650
ENST00000590685 ENSP00000468490
ENST00000588787 ENSP00000464896
ENST00000590400
ENST00000587317
ENST00000589359 ENSP00000468002
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006915 apoptotic process
GO:0008285 negative regulation of cell proliferation
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0043069 negative regulation of programmed cell death
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032194
View Gene Order
ENSBTAG00000009568
Not yet available
Cross-References
SwissProt
TrEMBL K7EL48
UniProt Splice Variant
Entrez Gene 25959
UniGene Hs.284208 Hs.598576 Hs.723365 Hs.742251
RefSeq NM_001136191 NM_015493
HUGO HGNC:29300
OMIM 614610
CCDS CCDS12255 CCDS54219
HPRD 12463
IMGT
EMBL AC009000 AC011485
GenPept
RNA Seq Atlas 102723473 25959

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca