Version 5.4
Homo sapiens Gene: HAUS1
Summary
InnateDB Gene IDBG-2917.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS1
Gene Name HAUS augmin-like complex, subunit 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152240
Encoded Proteins
IDBP-2919
HAUS augmin-like complex, subunit 1
IDBP-726233
IDBP-726542
IDBP-726412
IDBP-727254
IDBP-728115
IDBP-726007
IDBP-726486
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:46104332-46128333
Strand Forward strand
Band q21.1
Transcripts
ENST00000282058 ENSP00000282058
ENST00000595199
ENST00000591715 ENSP00000465093
ENST00000586060 ENSP00000466364
ENST00000591098
ENST00000585425
ENST00000593165 ENSP00000465622
ENST00000588704
ENST00000592471 ENSP00000468575
ENST00000589554 ENSP00000466715
ENST00000585518 ENSP00000467975
ENST00000592206 ENSP00000465492
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 34 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041840
View Gene Order
ENSBTAG00000002512
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_138443
HUGO
OMIM
CCDS CCDS11928
HPRD 16385
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca