Homo sapiens Gene: ELAVL3
Summary
InnateDB Gene IDBG-29474.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELAVL3
Gene Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
Synonyms HUC; HUCL; PLE21;
Species Homo sapiens
Ensembl Gene ENSG00000196361
Encoded Proteins
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:11451326-11481046
Strand Reverse strand
Band p13.2
Transcripts
ENST00000359227 ENSP00000352162
ENST00000438662 ENSP00000390878
ENST00000588853 ENSP00000467314
ENST00000592218
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0017091 AU-rich element binding
Biological Process
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.1701 Hs.607225 Hs.619756
RefSeq NM_001420 NM_032281 XM_006722683
HUGO
OMIM
CCDS CCDS32912 CCDS45978
HPRD 16024
IMGT
EMBL
GenPept
RNA Seq Atlas