Version 5.4
Mus musculus Gene: Elavl3
Summary
InnateDB Gene IDBG-143027.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elavl3
Gene Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
Synonyms 2600009P04Rik; Huc; mHuC; PLE21
Species Mus musculus
Ensembl Gene ENSMUSG00000003410
Encoded Proteins
IDBP-143029
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196361:
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:22015005-22052023
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000003501 ENSMUSP00000003501
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0017091 AU-rich element binding
Biological Process
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196361
View Gene Order
ENSBTAG00000014412
Not yet available
Cross-References
SwissProt Q60900
TrEMBL
UniProt Splice Variant
Entrez Gene 15571
UniGene Mm.390167 Mm.398084 Mm.408921 Mm.470676
RefSeq NM_010487 XM_006510021 XM_006510022
OMIM
CCDS CCDS52741
HPRD
IMGT
MGI ID MGI:109157
MGI Symbol Elavl3
EMBL BC052097 U29148 U29149
GenPept AAC52999 AAC53000 AAH52097
RNA Seq Atlas 15571

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca