Version 5.4
Homo sapiens Gene: NETO2
Summary
InnateDB Gene IDBG-29497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NETO2
Gene Name neuropilin (NRP) and tolloid (TLL)-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171208
Encoded Proteins
IDBP-29499
neuropilin (NRP) and tolloid (TLL)-like 2
IDBP-746504
IDBP-745833
IDBP-750474
IDBP-751071
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:47077703-47143997
Strand Reverse strand
Band q12.1
Transcripts
ENST00000303155 ENSP00000306726
ENST00000562559 ENSP00000454213
ENST00000562435 ENSP00000455169
ENST00000564667 ENSP00000457133
ENST00000563078 ENSP00000456818
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035255 ionotropic glutamate receptor binding
Biological Process
GO:2000312 regulation of kainate selective glutamate receptor activity
Cellular Component
GO:0014069 postsynaptic density
GO:0032983 kainate selective glutamate receptor complex
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036902
View Gene Order
ENSBTAG00000014370
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.645802 Hs.730937
RefSeq NM_001201477 NM_018092 XM_006721292
HUGO
OMIM
CCDS CCDS10727 CCDS58460
HPRD 09721
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca