Version 5.4
Homo sapiens Gene: SACM1L
Summary
InnateDB Gene IDBG-29621.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SACM1L
Gene Name SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms SAC1
Species Homo sapiens
Ensembl Gene ENSG00000211456
Encoded Proteins
IDBP-29623
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374316
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374320
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374322
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374324
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374325
SAC1 suppressor of actin mutations 1-like (yeast)
IDBP-374327
SAC1 suppressor of actin mutations 1-like (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:45689056-45745424
Strand Forward strand
Band p21.31
Transcripts
ENST00000389061 ENSP00000373713
ENST00000455997 ENSP00000389975
ENST00000418611 ENSP00000396387
ENST00000441228 ENSP00000406263
ENST00000438671 ENSP00000411966
ENST00000445499 ENSP00000403225
ENST00000433336 ENSP00000412883
ENST00000464524
ENST00000463237
ENST00000463347
ENST00000478586
ENST00000463659
ENST00000464102
ENST00000471207
ENST00000485311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004438 phosphatidylinositol-3-phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0034593 phosphatidylinositol bisphosphate phosphatase activity
GO:0042578 phosphoric ester hydrolase activity
GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0044281 small molecule metabolic process
GO:0046856 phosphatidylinositol dephosphorylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025240
View Gene Order
ENSBTAG00000003501
Not yet available
Pathways
NETPATH
REACTOME
REACT_121168
Synthesis of PIPs at the ER membrane pathway
REACT_120836
Synthesis of PIPs at the Golgi membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.156509 Hs.713970
RefSeq NM_014016
HUGO
OMIM
CCDS CCDS33745
HPRD 07587
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca