Homo sapiens Gene: CXCR6
Summary
InnateDB Gene IDBG-29993.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CXCR6
Gene Name chemokine (C-X-C motif) receptor 6
Synonyms BONZO; CD186; STRL33; TYMSTR;
Species Homo sapiens
Ensembl Gene ENSG00000172215
Encoded Proteins
chemokine (C-X-C motif) receptor 6
chemokine (C-X-C motif) receptor 6
chemokine (C-X-C motif) receptor 6
chemokine (C-X-C motif) receptor 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Mus musculus] Cxcl16-Cxcr6 crosstalk coordinates the intestinal topography of Il22 secretion required for mucosal defence against Citrobacter rodentium infection.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:45940933-45948353
Strand Forward strand
Band p21.31
Transcripts
ENST00000304552 ENSP00000304414
ENST00000438735 ENSP00000396218
ENST00000458629 ENSP00000395704
ENST00000457814 ENSP00000396886
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0015026 coreceptor activity
GO:0016494 C-X-C chemokine receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0019079 viral genome replication
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Peptide ligand-binding receptors pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
GPCR ligand binding pathway
KEGG
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O00574
TrEMBL A0N0N3
UniProt Splice Variant
Entrez Gene 10663
UniGene Hs.34526
RefSeq NM_006564 XM_005264809
HUGO HGNC:16647
OMIM 605163
CCDS CCDS2735
HPRD 05520
IMGT
EMBL AF007545 AF029759 AK313754 AY322543 BC033584 CH471055 EF064741 EU076974 U73529 U73531 Y13248
GenPept AAB61456 AAB61457 AAB64221 AAG21918 AAH33584 AAP84356 ABK41924 ABV02579 BAG36493 CAA73698 EAW64754
RNA Seq Atlas 10663