Homo sapiens Gene: CBLN1
Summary
InnateDB Gene IDBG-30226.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBLN1
Gene Name cerebellin 1 precursor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102924
Encoded Proteins
cerebellin 1 precursor
cerebellin 1 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:49277917-49281831
Strand Reverse strand
Band q12.1
Transcripts
ENST00000219197 ENSP00000219197
ENST00000536749 ENSP00000444651
ENST00000564786 ENSP00000455718
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007157 heterophilic cell-cell adhesion
GO:0007268 synaptic transmission
GO:0007399 nervous system development
GO:0009306 protein secretion
GO:0021707 cerebellar granule cell differentiation
GO:0051965 positive regulation of synapse assembly
Cellular Component
GO:0005576 extracellular region
GO:0030054 cell junction
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.458423
RefSeq NM_004352
HUGO
OMIM
CCDS CCDS10736
HPRD 02697
IMGT
EMBL
GenPept
RNA Seq Atlas